Massive Cache drive use (209GB) help

Appdata, isos, system and domains are the only things on the Cache drive, mover has been run and there is nothing on the cache drive that shouldn't be. I only have 1 docker installed currently (plex) and no VMs or ISOs downloaded or(no VMs). I have tried to delete old files that docker apps left behind, but some of the folders won't delete. ( I also have a share thsts empty but there are folders I can't delete (no files in them that I can see) and therfor can't remove the share)

I'm at a point where I want to restart my server from scratch, but don't want to loose the data on the drives in the array, can this be done? And if so, how?